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5721-91-5

(睪酮葵酸酯,testosterone decanoate--dea*schedule iii item)
睪酮葵酸酯結構式圖片|5721-91-5結構式圖片
睪酮葵酸酯
testosterone decanoate--dea*schedule iii item
5721-91-5
C29H46O3
442.673749446869
如需查看該化合物的詳細結構式,mol文件,smile,InChi 請點(diǎn)擊:睪酮葵酸酯結構式
睪酮葵酸酯MOL
155143

名稱(chēng)和標識符

MDLMFCD00133847
InChIKeyLBERVHLCXUMDOT-MPZZESAYSA-N
Inchi1S/C29H46O3/c1-4-5-6-7-8-9-10-11-27(31)32-26-15-14-24-23-13-12-21-20-22(30)16-18-28(21,2)25(23)17-19-29(24,26)3/h20,23-26H,4-19H2,1-3H3/t23-,24-,25-,26-,28-,29-/m0/s1
SMILESO(C(CCCCCCCCC)=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(CC[C@]4(C)[C@H]3CC[C@@]21C)=O

別名信息

- 中文別名 -

  • 睪酮葵酸酯
  • 癸酸睪酮
  • 癸酸睪丸素
  • 17β-羥基-4-雄甾烯-3-酮-17-癸酸酯
  • DEA限制
  • 睪酮癸酸酯
  • 睪酮癸酸酯,Testosterone decanoate
  • 睪酮癸烷
  • 癸酸睪酮 (甾體)
  • 癸酸睪酮 標準品
  • 癸酸睪酮(癸酸睪丸素)
  • 葵酸睪酮

- 英文別名 -

  • testosterone decanoate--dea*schedule iii item
  • Testosterone Decaonate
  • TESTOSTERONE 17-N-DECANOATE
  • testosterone caproate
  • TESTOSTERONE DECANOATE
  • 17-BETA-HYDROXY-4-ANDROSTEN-3-ONE-DECANOATE
  • 17b-hydroxyandrost-4-en-3-one decanoate
  • 4-ANDROSTEN-17BETA-OL-3-ONE 17-N-DECANOATE
  • 4-ANDROSTEN-17-BETA-OL-3-ONE DECANOATE
  • [(8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl] decanoate
  • Testosterone 17-Decanoate
  • 17beta-Hydroxyandrost-4-en-3-one decanoate
  • IJW60LAO6S
  • Testocaps (TN)
  • testosterone caprinate
  • UNII-IJW60LAO6S
  • Testosterone 17beta-decanoate
  • EINECS 227-226-4
  • CAS-5721-91-5
  • TESTOSTERONE DECANOATE [EP MONOGRAPH]
  • testosterone caprate
  • Testosterone decanoate for system suitability, European Pharmacopoeia (EP) Reference Standard
  • 5721-91-5
  • NSC 26642
  • Q27088963
  • DTXSID5046198
  • Tox21_111863
  • (17beta)-3-Oxoandrost-4-en-17-yl decanoate
  • Testosterone decanoate, European Pharmacopoeia (EP) Reference Standard
  • NSC26642
  • TESTOSTERONE DECANOATE [WHO-DD]
  • NCGC00160513-01
  • DS-3319
  • TESTOSTERONE DECANOATE [MART.]
  • 17.BETA.-HYDROXYANDROST-4-EN-3-ONE DECANOATE
  • D08573
  • Androst-4-en-3-one, 17-[(1-oxodecyl)oxy]-, (17.beta.)-
  • 3-OXOANDROST-4-EN-17.BETA.-YL DECANOATE
  • Testosterondecanoat
  • NSC-26642
  • Androst-4-en-3-one, 17-[(1-oxodecyl)oxy]-, (17b)-
  • GTPL7630
  • CHEMBL1473654
  • DTXCID3026198
  • Testosterone 17-Decanoate (1.0mg/ml in Acetonitrile)
  • W-105480
  • NS00015422
  • Test Decanoate
  • LBERVHLCXUMDOT-MPZZESAYSA-N
  • (1S,3aS,3bR,9aR,9bS,11aS)-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl decanoate
  • CHEBI:35000
  • BCP17658
  • SCHEMBL219795
  • AKOS015895429

物化性質(zhì)

實(shí)驗特性

LogP7.57080
PSA43.37000
折射率1.523
沸點(diǎn)539.2±50.0 °C at 760 mmHg
熔點(diǎn)38 °C
蒸氣壓0.0±1.4 mmHg at 25°C
閃點(diǎn)226.4±30.2 °C
顏色與性狀Powder
密度1.0±0.1 g/cm3

計算特性

精確分子量442.34500
氫鍵供體數量0
氫鍵受體數量3
可旋轉化學(xué)鍵數量10
同位素質(zhì)量442.345
重原子數量32
復雜度724
同位素原子數量0
確定原子立構中心數量6
不確定原子立構中心數量0
確定化學(xué)鍵立構中心數量0
不確定化學(xué)鍵立構中心數量0
共價(jià)鍵單元數量1
疏水參數計算參考值(XlogP)8
拓撲分子極性表面積43.4A^2

國際標準相關(guān)數據

EINECS227-226-4

專(zhuān)業(yè)數據庫參考

PubChemId155143

參考資料

Reaxys RN

睪酮葵酸酯 MSDS

基礎信息


Section 1. Chemical Product and Company Identification
    Testosterone Decanoate
    Common Name/
    Trade Name
    Manufacturer
    Commercial Name(s)
    Synonym
    Chemical Name
    Chemical Family
    Testosterone Decanoate

Section 4. First Aid Measures
    Eye Contact        Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at    
    least 15 minutes. Get medical attention if irritation occurs.
    Skin Contact        Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops.    
    Serious Skin Contact        Not available.    
    Inhalation        If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get    
    medical attention.
    Serious Inhalation        Not available.    
    Ingestion        Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an    
    unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight
    clothing such as a collar, tie, belt or waistband.
    Serious Ingestion        Not available.    

Section 5. Fire and Explosion Data
    Flammability of the Product May be combustible at high temperature.
    Auto-Ignition Temperature Not available.
    Flash Points        Not available.    
    Flammable Limits        Not available.    
    Products of Combustion        These products are carbon oxides (CO, CO2).    
    Fire Hazards in Presence of Slightly flammable to flammable in presence of heat.
    Various Substances        Non-flammable in presence of shocks.    
    Explosion Hazards in Presence Slightly explosive in presence of open flames and sparks.
    Non-explosive in presence of shocks.
    of Various Substances
    SMALL FIRE: Use DRY chemical powder.
    Fire Fighting Media
    and Instructions        LARGE FIRE: Use water spray, fog or foam. Do not use water jet.    
    As with most organic solids, fire is possible at elevated temperatures
    Special Remarks on
    Fire Hazards
    Special Remarks on Explosion Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust
    Hazards        explosion hazard.    

Section 6. Accidental Release Measures
    Small Spill        Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by    
    spreading water on the contaminated surface and dispose of according to local and regional authority
    requirements.
    Large Spill        Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water    
    on the contaminated surface and allow to evacuate through the sanitary system.
    Testosterone Decanoate

Section 7. Handling and Storage
    Precautions        Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not    
    breathe dust. Wear suitable protective clothing. If you feel unwell, seek medical attention and show the label
    when possible. Keep away from incompatibles such as oxidizing agents.
    Storage        Keep container tightly closed. Keep container in a cool, well-ventilated area. Sensitive to light. Store in    
    light-resistant containers.

Section 8. Exposure Controls/Personal Protection
    Engineering Controls        Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below    
    recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
    airborne contaminants below the exposure limit.
    Personal Protection        Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.    
    Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used
    a Large Spill        to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist    
    BEFORE handling this product.
    Exposure Limits        Not available.    

Section 9. Physical and Chemical Properties
    Physical state and appearance Solid. (Crystalline powder.)        Odor        Not available.    
    Taste        Not available.    
    Molecular Weight        442.68 g/mole    
    Color        White to yellowish.    
    pH (1% soln/water)        Not available.    
    Not available.
    Boiling Point
    Melting Point        48°C (118.4°F) - 54.2 C.    
    Not available.
    Critical Temperature
    Specific Gravity        Not available.    
    Vapor Pressure        Not applicable.    
    Vapor Density        Not available.    
    Volatility        Not available.    
    Odor Threshold        Not available.    
    Water/Oil Dist. Coeff.        Not available.    
    Ionicity (in Water)        Not available.    
    Dispersion Properties        Not available.    
    Solubility        Insoluble in cold water, hot water.    

Section 10. Stability and Reactivity Data
    The product is stable.
    Stability
    Instability Temperature        Not available.    
    Conditions of Instability        Excess heat, light, incompatible materials    
    Reactive with oxidizing agents.
    Incompatibility with various
    substances
    Not available.
    Corrosivity
    Testosterone Decanoate
    Sensitive to light.
    Special Remarks on
    Reactivity
    Not available.
    Special Remarks on
    Corrosivity
    Polymerization        Will not occur.    

Section 11. Toxicological Information
    Routes of Entry        Absorbed through skin. Inhalation. Ingestion.    
    Toxicity to Animals        LD50: Not available.    
    LC50: Not available.
    Chronic Effects on Humans        DEVELOPMENTAL TOXICITY: Classified Reproductive system/toxin/female, Reproductive system/toxin/male    
    [SUSPECTED].
    May cause damage to the following organs: blood, the reproductive system, liver.
    Other Toxic Effects on        Slightly hazardous in case of skin contact (irritant, permeator), of ingestion, of inhalation.    
    Humans
    Special Remarks on        Not available.    
    Toxicity to Animals
    Special Remarks on        May cause adverse reproductive effects and birth defects (teratogenic).    
    Chronic Effects on Humans        May cause cancer based on animal test data.    
    May affect genetic material (mutagenic)
    Special Remarks on other        Potential Effects of Overexposure:    
    Toxic Effects on Humans        Anabolic steroid    
    Skin: May cause skin irritation. May be absorbed through skin
    Eyes: Dust may cause eye irritation.
    Inhalation: Dust may cause respiratory tract irritaiton.
    Ingestion: May cause gastrointestinal tract irritation with upset stomach or stomach pain, nausea, vomiting,
    diarrhea. May cause water and salt retention (edema), weight gain, acne and muscular development. Other
    symptoms may include headache, unusual tiredness, dizziness, trouble sleeping, increased pubic hair growth,
    change in sex drive. Females may also experience virilizing side effects such as facial hair, deepening of the
    voice, and menstrual irregularities. Effects of chronic overexposure in women include male-pattern baldness,
    excessive body hair, prominant musculature, and hypertrophy of the clitoris, decreased breast size, oily skin,
    impaired fertility. Effects generally slowly subside on discontinuation of exposure, but with prolonged
    overexposure in women some effects may become irreversible. Overexposure in males may lead to feminizing
    side effects (breast enlargement and or soreness), and decreased spermatogenesis or impaired fertility due to
    inhibition of gonadotropin secretion and metabolic conversion of androgens to estrogens. Other symptoms of
    overexposure in males may include frequent or continuing erections, chills, pain in the scrotum or groin, difficulty
    urinating, decreased testicle size, and aggressive behavior.
    May also affect blood(clotting disorders, elevated cholesterol levels, change in red blood cell count), and liver.
    Effects on the liver may cause yellowing of the skin or eyes (jaundice).
    Chronic exposure may cause hypersensitization, masculinization in females, heart problems in males, impaired
    fertility in males and females and cancer.
    Medical Conditions Aggravated by Exposure: Hypersensitivity to material, males with breast or prostate cancer,
    hypercalcemia resulting from osteolysis, pre-exisiting liver, kidney, or heart problems, and enlarged prostate gland.

Section 12. Ecological Information
    Ecotoxicity        Not available.    
    BOD5 and COD        Not available.    
    Products of Biodegradation        Possibly hazardous short term degradation products are not likely. However, long term degradation products may    
    arise.
    Toxicity of the Products        The product itself and its products of degradation are not toxic.    
    of Biodegradation
    Special Remarks on the        Not available.    
    Products of Biodegradation
    Testosterone Decanoate

Section 13. Disposal Considerations
    Waste Disposal        Waste must be disposed of in accordance with federal, state and local environmental    
    control regulations.

Section 14. Transport Information
    DOT Classification        Not a DOT controlled material (United States).    
    Not applicable.
    Identification
    Not applicable.
    Special Provisions for
    Transport
    DOT (Pictograms)

Section 15. Other Regulatory Information and Pictograms
    California prop. 65: This product contains the following ingredients for which the State of California has found to
    Federal and State
    cause cancer, birth defects or other reproductive harm, which would require a warning under the statute:
    Regulations
    Testosterone Decanoate
    California prop. 65: This product contains the following ingredients for which the State of California has found to
    cause reproductive harm (female) which would require a warning under the statute: Testosterone Decanoate
    California prop. 65: This product contains the following ingredients for which the State of California has found to
    cause reproductive harm (male) which would require a warning under the statute: Testosterone Decanoate
    California prop. 65: This product contains the following ingredients for which the State of California has found to
    cause cancer which would require a warning under the statute: Testosterone Decanoate
    California        California prop. 65: This product contains the following ingredients for which the State of California has found    
    Proposition 65        to cause cancer which would require a warning under the statute: Testosterone Decanoate    
    Warnings
    California prop. 65: This product contains the following ingredients for which the State of California has found
    to cause birth defects which would require a warning under the statute: No products were found.
    Other Regulations        OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).    
    EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances.
    Other Classifications        WHMIS (Canada) Not Available    
    DSCL (EEC)        R45- May cause cancer.        S36/37- Wear suitable protective clothing and    
    R63- Possible risk of harm to the        gloves.    
    unborn child.        S46- If swallowed, seek medical advice    
    immediately and show this container or label.
    S53- Avoid exposure - obtain special
    instructions before use.
    Health Hazard
    HMIS (U.S.A.)        1 National Fire Protection    
    1 Flammability
    1 Association (U.S.A.)
    Fire Hazard
    1 0 Reactivity
    Health
    Reactivity
    0
    Specific hazard
    Personal Protection
    E
    WHMIS (Canada)
    (Pictograms)
    Testosterone Decanoate
    DSCL (Europe)
    (Pictograms)
    TDG (Canada)
    (Pictograms)
    ADR (Europe)
    (Pictograms)
    Protective Equipment
    Gloves.
    Lab coat.
    Dust respirator. Be sure to use an
    approved/certified respirator or
    equivalent. Wear appropriate respirator
    when ventilation is inadequate.


SECTION 16 - ADDITIONAL INFORMATION
N/A
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